ea0014oc1.1 | Thyroid clinical | ECE2007
Cordella Daniela
, Marco Alessandro De
, Calebiro Davide
, Filippis Tiziana de
, Radetti Giorgio
, Weber Giovanna
, Vigone Maria Cristina
, Cappa Marco
, Sartorio Alessandro
, Busnelli Marta
, Bonomi Marco
, Chini Bice
, Beck-Peccoz Paolo
, Persani Luca
Mild hypothyroidism is a heterogeneous and frequent disorder in the general population that is due to autoimmune disease in most of the cases. TSH resistance is considered a rare genetic disease due to germline loss-of-function TSHR mutations. However, TSHR mutations have been mainly searched in patients with large TSH elevations and their actual prevalence among patients with mild TSH elevations (as those found in mild hypothyroidism) is so far unknown. In this study, we eval...